The Peer Network FAQs

The Peer Network FAQS
The Peer Network FAQs

United Therapeutics Corporation established the PEER Network in May 2007 to provide support for those with pulmonary arterial hypertension (PAH).

It is a resource for patients, and their caregivers, who are considering or starting one of the following treatments: 

  • Remodulin® (treprostinil) Injection
  • Tyvaso® (treprostinil) Inhalation Solution
  • Orenitram® (treprostinil) Extended-Release Tablets

The PEER Network connects new patients (“Mentees”) with those who have already experienced what it’s like to incorporate PAH medication into their daily routine (“Mentors”).

How will I use the PEER Network?

As a Mentee, you will connect with your Mentor over the phone. Mentors are available to share their personal experiences about their day-to-day experiences with Remodulin, Tyvaso, or Orenitram.

Please keep in mind, Mentors do not offer medical advice. So, if you have medical questions, or specific questions about your treatment, be sure to bring those up with your doctor.

What if I live outside the United States of America?

We’re sorry, but the PEER Network is for United States residents only. 

Who are the PEER Mentors?

The PEER Mentors are volunteer patients and caregivers who know what it’s like to navigate life with pulmonary arterial hypertension (PAH). They’re here to provide lifestyle tips and guidance for others with PAH who are considering (or currently receiving) treatment with Remodulin, Tyvaso, or Orenitram.

What if I want to change Mentors?

If, for any reason, you’d like to connect with a different Mentor, please email or call 866-505-7337. PEER Network staff will deactivate your current Mentor relationship and help you re-register and choose a new Mentor.

How do I register to become a Mentee?

  1. Click on Connect with a Mentor anywhere on the site
  2. Select if you wish to communicate with a Remodulin, Tyvaso, or Orenitram Mentor
  3. Fill out a registration form and hit submit
  4. You’ll see a Thank You screen confirming that we’ve received your registration
  5. A member of the PEER Network staff will contact you and arrange a phone conversation with your Mentor

How do I start communicating with a Mentor?

First, make sure you have completed your registration.

After submitting your registration, someone from the PEER Network staff will contact you and ask a few questions before connecting you with a Mentor. Then, the PEER Network staff will search for a Mentor who best suits your needs. The staff member will contact the Mentor to make sure they’re available and arrange for a toll-free call. After your first call with your Mentor, someone from the PEER Network staff will check in with you to make sure you were satisfied with your experience.

Does it cost anything for me to communicate with a PEER Mentor?

No, there is no charge to join the PEER Network and communicate with a Mentor.

How long can I communicate with my Mentor?

Our program allows for a 4-month maximum communication period between you and your Mentor. Once the 4 months are up, you can choose a new Mentor or ask if your previous Mentor is still available. At this time, you can also consider becoming a Mentor yourself.

Am I allowed to communicate with more than one Mentor at a time?

You’re only allowed to communicate with one PEER Mentor at any given time. If you’d like to change your Mentor, contact the PEER Network at or call 866-505-7337. 

How do I become a Mentor?

Volunteer PEER Mentors must be diagnosed with PAH (WHO Group I) and currently taking Remodulin, Tyvaso, or Orenitram for an approved indication for at least four months. Mentors can also be the caregiver of a patient as described above.

If this sounds like you and you’re interested in helping other patients and/or caregivers, register online, call 866-505-7337, or contact the PEER Network via email at for more information.

Can I opt out of the PEER Network after registering?

Yes, you can opt out of the program at any time by emailing or calling 866-505-7337. 

Do you keep my information private after I’ve registered?

Yes, any information you provide while registering is kept private. Your personal information is not used, sold, or assigned for any purpose other than to communicate with you about the PEER Network program and as otherwise required by law. For full information, please see our Privacy Policy

Who is the PEER Network sponsored by?

The PEER Network is sponsored exclusively by United Therapeutics Corporation, the manufacturer of Remodulin, Tyvaso and Orenitram.

What is Remodulin® (treprostinil) Injection?

Remodulin mimics some of the effects of the natural prostacyclin that your body lacks, making it easier for your heart to pump blood through your lungs. Remodulin may help improve exercise-related PAH symptoms, including shortness of breath and fatigue.

You may experience side effects when taking Remodulin In clinical studies of SC infusion of Remodulin, most people experienced infusion site pain and infusion site reaction (redness and swelling). These symptoms were often severe and sometimes required treatment with narcotics or discontinuation of Remodulin. The IV infusion of Remodulin has been associated with the risk of blood stream infections, arm swelling, tingling sensations, bruising, and pain. Other common side effects seen with either SC or IV Remodulin were headache, diarrhea, jaw pain, nausea, vasodilatation (widening of the blood vessels), and edema (swelling).

Please see the Full Prescribing Information for Remodulin.

For additional information about Remodulin, visit or call 1-877-UNITHER (1-877-864-8437).

What is Tyvaso® (treprostinil) Inhalation Solution?

Tyvaso is a prescription medicine used in adults to treat pulmonary arterial hypertension (PAH) (WHO Group 1), which is high blood pressure in the arteries of your lungs. Tyvaso can improve exercise ability in people who also take bosentan (an endothelin receptor antagonist) or sildenafil (a phosphodiesterase-5 inhibitor). The effects decrease over 4 hours; treatment timing can be adjusted for planned activities.

Tyvaso is an inhaled medication, meaning it is breathed in through the mouth and directly into the lungs. It is a synthetic (man-made) form of prostacyclin called a prostacyclin analogue. Prostacyclin is a chemical made naturally by the body. People with PAH lack enough natural prostacyclin for normal lung function. In the body, Tyvaso mimics some of the effects of natural prostacyclin, helping to open up the arteries in the lungs and make it easier for the heart to pump blood through them. In the clinical trial, patients who added Tyvaso to their oral therapy were able to increase their exercise ability by an average of 20 meters, as shown by their 6-minute walk distance (6MWD).

You may experience side effects when taking Tyvaso

The most common side effects of Tyvaso include the following:  

  • Cough
  • Headache  
  • Throat irritation and pain  
  • Nausea  
  • Reddening of your face and neck (flushing)  
  • Fainting or loss of consciousness

Please see the Full Prescribing Information, Patient Product Information, and the Tyvaso Inhalation System Instructions for Use manual. (TD-100 or TD-300).

For additional information about Tyvaso, visit or call 1-877-UNITHER (1-877-864-8437). 

What is Orenitram® (treprostinil) Extended-Release Tablets?

Orenitram is the only FDA-approved prostacyclin analogue in a tablet to treat PAH and has been shown to improve exercise ability (or walking distance).

In a 12-week study of 349 patients with PAH not currently receiving any other PAH therapy, patients on Orenitram showed improvement in their 6-minute walk distance compared with patients on placebo (a pill without active ingredients).

With Orenitram, there is information available for your healthcare team about how patients stable on pump therapy (treprostinil) transitioned to oral therapy. It is not known if Orenitram is safe and effective in children under 18 years of age.

Orenitram is the only pill that gives you the same type of medicine (active ingredient) that is available in pump therapy.

Because Orenitram is an oral option, you may enjoy activities like being in the pool or taking a bath. Taking Orenitram may improve your ability to exercise. This means you could see improvement in physical activities, such as walking to the mailbox.

You may experience side effects when taking Orenitram

Some of the most common side effects experienced by people taking Orenitram include
• Headache       • Nausea       • Diarrhea      • Flushing    

Please see the Full Prescribing Information or Patient Information for Orenitram.

For additional information about Orenitram, visit or call 1-877-UNITHER (1-877-864-8437).

What is United PAH Support?

Created by United Therapeutics, United PAH Support connects patients and caregivers to information about PAH, including treatment options, support outlets, and educational resources.

To learn more about United PAH Support, visit